Chemistry

Albumin-Corrected Anion Gap

Anion gap adjusted for low albumin.

Education and reference only. Not a substitute for clinical judgement, local policy or product labelling. Always verify before clinical use. Values are calculated in your browser and never stored.

When to use

Use when albumin is low, since hypoalbuminaemia lowers the measured anion gap and can mask a high-anion-gap acidosis.

Why use

It unmasks a raised anion gap that low albumin would otherwise hide.

Critical actions

Correction adds ~2.5 mmol/L per 1 g/dL fall in albumin below 4. Albumin in g/dL (divide g/L by 10).

Evidence & references

  1. Figge J et al. Anion gap and hypoalbuminemia. Crit Care Med. 1998.

Related calculators

Anion GapSerum anion gap for metabolic acidosis.Delta Ratio (Acid–Base)Detects mixed metabolic acid–base disorders.Winters' FormulaExpected pCO₂ in metabolic acidosis.

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