Hepatology

FIB-4 Index

Non-invasive estimate of liver fibrosis.

Education and reference only. Not a substitute for clinical judgement, local policy or product labelling. Always verify before clinical use. Values are calculated in your browser and never stored.

When to use

Use as a first-line, non-invasive screen for advanced fibrosis (e.g. in NAFLD), to decide who needs specialist assessment.

Why use

It rules out advanced fibrosis simply, reducing unnecessary referrals.

Evidence & references

Sterling RK et al. Development of a simple noninvasive index to predict significant fibrosis in HIV/HCV co-infection. Hepatology. 2006.

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