Endocrinology

HOMA-IR

Estimate of insulin resistance.

Education and reference only. Not a substitute for clinical judgement, local policy or product labelling. Always verify before clinical use. Values are calculated in your browser and never stored.

When to use

Use to estimate insulin resistance from fasting glucose and insulin, mainly in research and selected clinical contexts.

Why use

It gives a simple index of insulin resistance.

Critical actions

HOMA-IR = (fasting glucose mmol/L × fasting insulin mU/L) / 22.5. Thresholds vary by population and assay; interpret with caution.

Evidence & references

  1. Matthews DR et al. Homeostasis model assessment. Diabetologia. 1985.

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