Critical Care

SIRS Criteria

Systemic inflammatory response syndrome.

Education and reference only. Not a substitute for clinical judgement, local policy or product labelling. Always verify before clinical use. Values are calculated in your browser and never stored.

When to use

Use to identify a systemic inflammatory response; ≥2 criteria with suspected infection historically defined sepsis (now superseded by Sepsis-3).

Why use

It remains a quick screen, though qSOFA/Sepsis-3 are now preferred for sepsis.

Advice

With suspected infection, consider sepsis and assess with qSOFA / full clinical picture; SIRS alone is non-specific.

Evidence & references

  1. Bone RC et al. Definitions for sepsis and organ failure. Chest. 1992.

Related calculators

qSOFA ScoreQuick bedside flag for poor outcome in suspected infection.NEWS2 (National Early Warning Score 2)Standardised UK early-warning score for acute illness.

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