Mental health

Medicines for Dissociative disorders

Mental health conditions involving a sense of disconnection from oneself, one’s surroundings, memories, or identity — often linked to trauma, and helped by talking therapies and support.

Education and reference only. This explains which medicines are used and why, in plain language — it deliberately contains no doses and is not a substitute for advice from your doctor or pharmacist. Always discuss your own treatment with a qualified clinician, and check the BNF and the product labelling for prescribing detail.

Quick answer

What is Dissociative disorders?

Dissociative disorders are a group of mental health conditions that involve dissociation — a sense of disconnection or detachment from oneself, one’s thoughts, feelings, memories, surroundings, sense of identity, or a combination of these. Dissociation is, to some degree, a normal experience that many people have at times (such as "switching off", daydreaming, or feeling detached briefly, for example when very stressed or tired).

  • How it is treated: Dissociative disorders are managed mainly with psychological therapy (talking therapies), often focusing on safety, understanding and managing the dissociation, and processing any underlying trauma, along with support and treating any co-occurring conditions; recovery and improvement are possible.
  • Self-care: For dissociative disorders: accessing psychological therapy (talking therapies) is central — often focusing on safety, managing the dissociation (with grounding and other techniques to stay connected to the present), and, where relevant, processing underlying trauma.
  • When to seek help: See a GP if you experience persistent or distressing dissociation — feeling detached from yourself, your body, or your surroundings, gaps in memory beyond ordinary forgetfulness, or other experiences of disconnection — that affects your life, so it can be assessed and support and therapy arranged.

What it is

Dissociative disorders are a group of mental health conditions that involve dissociation — a sense of disconnection or detachment from oneself, one’s thoughts, feelings, memories, surroundings, sense of identity, or a combination of these. Dissociation is, to some degree, a normal experience that many people have at times (such as "switching off", daydreaming, or feeling detached briefly, for example when very stressed or tired). It becomes a disorder when it is persistent, distressing, or interferes with a person’s life. Dissociation is often understood as a way the mind copes with overwhelming experiences — it is frequently linked to trauma, particularly severe, repeated, or early-life trauma (such as abuse), acting as a way of coping by disconnecting from distressing experiences or feelings. There are several types of dissociative disorder, which can involve different experiences, such as: feeling detached from oneself or one’s body, as if observing oneself from outside (depersonalisation), or feeling that the surroundings are unreal or dreamlike (derealisation); gaps in memory, particularly for personal information or events, that are more than ordinary forgetfulness (dissociative amnesia); and, in some, experiencing distinct, separate parts or identities (as in dissociative identity disorder, previously called multiple personality disorder). Dissociation can be frightening, confusing, and distressing, and can significantly affect a person’s sense of self, memory, functioning, and daily life. Dissociative disorders can occur alongside other mental health conditions (such as PTSD, depression, or anxiety). It is important to understand that dissociative disorders are recognised mental health conditions, often a response to difficult experiences, and that they can be helped: the main treatment is psychological therapy (talking therapies), often with a focus on safety, understanding and managing the dissociation, and, where relevant, processing the underlying trauma, along with support. Support from mental health services helps, and recovery and improvement are possible with appropriate help. The key messages are that dissociative disorders involve a distressing sense of disconnection from oneself, surroundings, memories, or identity, often linked to trauma, and that talking therapies and support help.

How it is treated

Dissociative disorders are managed mainly with psychological therapy (talking therapies), often focusing on safety, understanding and managing the dissociation, and processing any underlying trauma, along with support and treating any co-occurring conditions; recovery and improvement are possible. Because dissociative disorders are recognised mental health conditions, and because dissociation can be distressing and confusing, an important step is recognising the difficulty and seeking help — a GP can be a starting point, providing support, assessing the situation, and arranging referral to appropriate mental health services, which assess the dissociation and any related difficulties. The main treatment is psychological therapy, tailored to the individual and the type and severity of dissociation. Therapy often focuses on: establishing safety and stability, and helping the person manage the dissociation and any distressing symptoms (with grounding techniques and other strategies to help stay connected to the present and manage episodes of dissociation); understanding the dissociation and its role (often as a way of coping with overwhelming experiences); and, where relevant and when the person is ready, working with the underlying trauma or difficult experiences that often lie behind dissociation, in a careful, paced way. Different therapeutic approaches are used, and therapy for dissociative disorders (particularly the more complex forms) is often specialised and takes time. Support for any co-occurring conditions — such as PTSD, depression, or anxiety, which often occur alongside dissociative disorders — is important, and these are treated as part of care. Building coping strategies, support, and a sense of safety and stability in the person’s life are part of the approach. Support from mental health services, and, where relevant, specialist services for complex or trauma-related dissociation, helps, and support organisations provide information and peer support. Because dissociative disorders are often linked to trauma and can be distressing, a compassionate, understanding approach is important, and it is important to seek help promptly if there are thoughts of self-harm or suicide, which can occur. With appropriate psychological therapy and support, people with dissociative disorders can be helped to understand and manage their experiences, process underlying difficulties, and improve their wellbeing and functioning, and recovery and improvement are possible, though it can take time. The reassuring messages are that dissociative disorders are recognised, treatable mental health conditions, often a response to difficult or traumatic experiences, that talking therapies (with support and treatment of any co-occurring conditions) help people understand and manage the dissociation and, where relevant, process the underlying trauma, and that recovery and improvement are possible; so seeking help, and accessing psychological therapy and support, are the keys to managing dissociative disorders.

For this condition, these medicines

Medicine classes used for Dissociative disorders

Each links to a full, dose-free guide — what it is, how it works, who can and cannot use it, side effects, interactions and FAQs.

Beyond medication

Lifestyle and self-care

For dissociative disorders: accessing psychological therapy (talking therapies) is central — often focusing on safety, managing the dissociation (with grounding and other techniques to stay connected to the present), and, where relevant, processing underlying trauma. Support for any co-occurring conditions (such as PTSD, depression, or anxiety), building coping strategies and a sense of safety and stability, and support from services and organisations all help. Recovery and improvement are possible.

When to get help

When to see a doctor

See a GP if you experience persistent or distressing dissociation — feeling detached from yourself, your body, or your surroundings, gaps in memory beyond ordinary forgetfulness, or other experiences of disconnection — that affects your life, so it can be assessed and support and therapy arranged. Seek urgent help if you have thoughts of harming yourself or of suicide (call 999, a crisis line, or the Samaritans on 116 123).

999Emergency — call 999 or go to A&E
111Urgent advice — call NHS 111 or use 111 online
GPNon-urgent — see your GP or pharmacist

Not sure how urgent it is? It is always OK to call NHS 111 for advice, day or night.

Answers

Dissociative disorders: frequently asked questions

What are dissociative disorders?

Mental health conditions involving dissociation — a persistent, distressing sense of disconnection or detachment from oneself, one’s thoughts, feelings, memories, surroundings, or identity. They can involve feeling detached from oneself or one’s body (depersonalisation), feeling that surroundings are unreal (derealisation), gaps in memory (dissociative amnesia), or, in some, experiencing separate parts or identities. They are often linked to trauma.

Can dissociative disorders be treated?

Yes — the main treatment is psychological therapy (talking therapies), often focusing on safety, understanding and managing the dissociation (with grounding and other techniques), and, where relevant, carefully processing any underlying trauma, along with support and treating any co-occurring conditions (such as PTSD, depression, or anxiety). Recovery and improvement are possible, though it can take time. Seeking help is worthwhile.

Building a patient-information or formulary resource?

We create evidence-led, dose-free clinical references and decision aids for teams.

☎ Call Get a Proposal