Ear, nose and throat
Medicines for Epiglottitis
A rare but life-threatening swelling of the flap above the voice box that can block breathing — a medical emergency needing immediate hospital care.
Education and reference only. This explains which medicines are used and why, in plain language — it deliberately contains no doses and is not a substitute for advice from your doctor or pharmacist. Always discuss your own treatment with a qualified clinician, and check the BNF and the product labelling for prescribing detail.
Quick answer
What is Epiglottitis?
Epiglottitis is inflammation and swelling of the epiglottis — the small flap of tissue at the base of the tongue that closes over the windpipe when swallowing to stop food going into the airway. When it becomes severely swollen, usually from infection, it can rapidly block the airway, making it a life-threatening emergency.
- How it is treated: Epiglottitis is a medical emergency and must be managed in hospital without delay.
- Self-care: Prevention rests largely on childhood Hib vaccination, which has greatly reduced the classic form.
- When to seek help: Call 999 immediately for a severe sore throat with difficulty breathing, drooling (unable to swallow saliva), a muffled voice, high fever, and a person sitting upright struggling to breathe — epiglottitis is a life-threatening emergency.
What it is
Epiglottitis is inflammation and swelling of the epiglottis — the small flap of tissue at the base of the tongue that closes over the windpipe when swallowing to stop food going into the airway. When it becomes severely swollen, usually from infection, it can rapidly block the airway, making it a life-threatening emergency. It was more common in young children before the Hib vaccine (which protects against a common cause) greatly reduced it; it can still occur in children and, increasingly, in adults. Symptoms come on quickly and can include a severe sore throat, difficulty and pain when swallowing (with drooling because swallowing is too painful), a muffled or "hot potato" voice, a high fever, and difficulty breathing, often with the person sitting upright and leaning forward to breathe. Because it can progress fast, it is treated as an emergency.
How it is treated
Epiglottitis is a medical emergency and must be managed in hospital without delay. The priority is protecting the airway, so a person with suspected epiglottitis should be kept calm and upright and taken for emergency care, avoiding anything that might distress them or examine the throat (which could trigger complete blockage). In hospital, the airway is secured by experienced specialists if needed, oxygen is given, and antibiotics treat the underlying infection, along with supportive care. Most people recover well with prompt treatment. Prevention through the Hib vaccination in the childhood immunisation schedule has made the classic childhood form much rarer. The essential message is recognition and immediate emergency response, given how quickly the airway can be threatened.
For this condition, these medicines
Medicine classes used for Epiglottitis
Each links to a full, dose-free guide — what it is, how it works, who can and cannot use it, side effects, interactions and FAQs.
Beyond medication
Lifestyle and self-care
Prevention rests largely on childhood Hib vaccination, which has greatly reduced the classic form. The key practical point is recognising the warning signs and seeking emergency help immediately, keeping the person calm and upright.
When to get help
When to see a doctor
Call 999 immediately for a severe sore throat with difficulty breathing, drooling (unable to swallow saliva), a muffled voice, high fever, and a person sitting upright struggling to breathe — epiglottitis is a life-threatening emergency. Keep them calm and upright; do not try to examine the throat.
Not sure how urgent it is? It is always OK to call NHS 111 for advice, day or night.
Answers
Epiglottitis: frequently asked questions
Why is epiglottitis an emergency?
Because severe swelling of the epiglottis can rapidly block the airway, making it life-threatening. Difficulty breathing, drooling, a muffled voice and a severe sore throat with high fever need an immediate 999 call.
How is epiglottitis prevented?
The Hib vaccine in the childhood immunisation schedule protects against a common cause and has made the classic childhood form much rarer.
Keep reading
Related articles
Sources
Where this is drawn from
- NHS — Epiglottitis
- UKHSA — Hib guidance
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