Skin

Medicines for Intertrigo

A red, sore rash in skin folds caused by friction, moisture and warmth, often with added infection — managed by keeping the area cool and dry and treating any infection.

Education and reference only. This explains which medicines are used and why, in plain language — it deliberately contains no doses and is not a substitute for advice from your doctor or pharmacist. Always discuss your own treatment with a qualified clinician, and check the BNF and the product labelling for prescribing detail.

Quick answer

What is Intertrigo?

Intertrigo is inflammation of the skin in body folds — such as under the breasts, in the groin, the armpits, the tummy folds, and between the toes — caused by skin rubbing against skin in a warm, moist environment. The friction, trapped sweat and lack of air breakdown the skin, causing a red or discoloured, sore, sometimes itchy or stinging rash, which can become cracked, weepy or smelly.

  • How it is treated: Management focuses on reducing the friction and moisture that cause the problem, and treating any infection.
  • Self-care: Keeping skin folds clean and dry (washing gently and drying thoroughly), wearing loose breathable clothing, reducing friction and moisture (barrier creams, allowing air), managing weight, blood sugar and sweating, and treating any infection all help intertrigo and prevent recurrence.
  • When to seek help: See a GP or pharmacist about a persistent sore rash in a skin fold, especially if it is not improving with keeping the area clean and dry, is spreading, weepy or smelly (suggesting infection), or if you have diabetes or a weakened immune system.

What it is

Intertrigo is inflammation of the skin in body folds — such as under the breasts, in the groin, the armpits, the tummy folds, and between the toes — caused by skin rubbing against skin in a warm, moist environment. The friction, trapped sweat and lack of air breakdown the skin, causing a red or discoloured, sore, sometimes itchy or stinging rash, which can become cracked, weepy or smelly. Because the warm, moist folds are an ideal environment for microbes, intertrigo is frequently complicated by infection — often a yeast (candida), and sometimes bacteria — which adds to the redness, soreness and any discharge or odour. It is more common in people who are overweight (with deeper folds), in warm or humid conditions, with sweating, diabetes, reduced mobility, or incontinence. It is uncomfortable but manageable, and identifying and treating any infection is an important part of care.

How it is treated

Management focuses on reducing the friction and moisture that cause the problem, and treating any infection. Key measures include keeping the affected folds clean and dry — gently washing and thoroughly drying (patting, not rubbing), and allowing air to the area where possible — and reducing friction and moisture (for example with loose, breathable clothing, and sometimes barrier creams or moisture-absorbing measures). Where infection is present, it is treated: an antifungal cream for a yeast infection (common), or an antibacterial treatment for bacterial infection, and sometimes a short course of a mild anti-inflammatory treatment to settle the inflammation. Managing contributing factors — such as weight, blood sugar in diabetes, sweating, and incontinence — helps prevent recurrence, which is common. If it is severe, widespread, not improving, or the diagnosis is uncertain, a doctor can advise. The reassuring message is that intertrigo is manageable with good skin care and treating any infection, though it can recur if the underlying factors remain.

For this condition, these medicines

Medicine classes used for Intertrigo

Each links to a full, dose-free guide — what it is, how it works, who can and cannot use it, side effects, interactions and FAQs.

Beyond medication

Lifestyle and self-care

Keeping skin folds clean and dry (washing gently and drying thoroughly), wearing loose breathable clothing, reducing friction and moisture (barrier creams, allowing air), managing weight, blood sugar and sweating, and treating any infection all help intertrigo and prevent recurrence.

When to get help

When to see a doctor

See a GP or pharmacist about a persistent sore rash in a skin fold, especially if it is not improving with keeping the area clean and dry, is spreading, weepy or smelly (suggesting infection), or if you have diabetes or a weakened immune system.

999Emergency — call 999 or go to A&E
111Urgent advice — call NHS 111 or use 111 online
GPNon-urgent — see your GP or pharmacist

Not sure how urgent it is? It is always OK to call NHS 111 for advice, day or night.

Answers

Intertrigo: frequently asked questions

What causes a rash in skin folds?

Intertrigo is caused by skin rubbing against skin in warm, moist folds, with friction, trapped sweat and lack of air breaking down the skin. It is often complicated by infection (frequently a yeast), which adds to the redness and soreness.

How is intertrigo treated?

By keeping the folds clean and dry, reducing friction and moisture, and treating any infection (antifungal for yeast, antibacterial for bacteria), sometimes with a mild anti-inflammatory. Managing weight, diabetes and sweating helps prevent recurrence.

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