Mental health

Medicines for Loneliness

The distressing feeling of being alone or disconnected from others, which is common and can affect mental and physical health — helped by connection, support and practical steps.

Education and reference only. This explains which medicines are used and why, in plain language — it deliberately contains no doses and is not a substitute for advice from your doctor or pharmacist. Always discuss your own treatment with a qualified clinician, and check the BNF and the product labelling for prescribing detail.

Quick answer

What is Loneliness?

Loneliness is the unpleasant feeling that arises when there is a gap between the social connections a person has and the connections they want — feeling alone, isolated, or disconnected from others, even sometimes when among people. It is common, and anyone can experience it at any age.

  • How it is treated: Addressing loneliness involves finding ways to build meaningful connection and support, and there are many approaches, which can be tailored to a person’s circumstances and preferences.
  • Self-care: Reaching out to existing friends and family, finding opportunities to meet others through groups, classes, volunteering or community activities, using local befriending and support services, doing enjoyable and meaningful activities, and being physically active all help build connection and reduce loneliness.
  • When to seek help: See a GP if loneliness is persistent and affecting your mood, wellbeing or daily life, or if you have symptoms of depression or anxiety, such as persistent low mood or loss of interest.

What it is

Loneliness is the unpleasant feeling that arises when there is a gap between the social connections a person has and the connections they want — feeling alone, isolated, or disconnected from others, even sometimes when among people. It is common, and anyone can experience it at any age. Loneliness is not the same as being alone: some people are content with little social contact, while others feel lonely despite being around others. It can be temporary, triggered by particular circumstances (such as moving, a bereavement, a relationship ending, retirement, becoming a parent, illness, or a change in circumstances), or more persistent. Loneliness is a normal human emotion and not a mental illness, but persistent loneliness can affect wellbeing — it is linked with a higher risk of mental health problems such as depression and anxiety, and can affect physical health too, so it is important to take it seriously and address it. There is often a stigma around admitting to feeling lonely, which can make it harder to reach out, but it is a common experience and nothing to be ashamed of. The encouraging message is that there are many ways to build connection and to feel less lonely — through relationships, activities, communities, and support — and that help and resources are available, so loneliness can be addressed.

How it is treated

Addressing loneliness involves finding ways to build meaningful connection and support, and there are many approaches, which can be tailored to a person’s circumstances and preferences. Helpful steps include: reaching out to existing contacts — reconnecting with friends or family, or making the effort to keep in touch; finding opportunities to meet others and build new connections — for example through groups, classes, clubs, volunteering, community or faith activities, shared interests or hobbies, which bring people together around common ground; and using local and online resources — many communities have activities, befriending schemes, and support services, and organisations offer help and information for people experiencing loneliness. Doing enjoyable and meaningful activities, being physically active, and looking after wellbeing also help. Small steps can make a difference, and it is worth being patient and kind to yourself, as building connection takes time. Because loneliness is linked with mental health, it is important to see a GP if loneliness is persistent and affecting your mood or wellbeing, or if you have symptoms of depression or anxiety — support, talking therapies, and social prescribing (connecting people with community activities and support) can help. Addressing any circumstances contributing to isolation, and seeking practical support where relevant, are also part of the picture. The reassuring message is that loneliness is common and nothing to be ashamed of, that there are many ways to build connection and feel less lonely, and that support and resources are available — so reaching out, in whatever way feels manageable, is a positive step.

For this condition, these medicines

Medicine classes used for Loneliness

Each links to a full, dose-free guide — what it is, how it works, who can and cannot use it, side effects, interactions and FAQs.

Beyond medication

Lifestyle and self-care

Reaching out to existing friends and family, finding opportunities to meet others through groups, classes, volunteering or community activities, using local befriending and support services, doing enjoyable and meaningful activities, and being physically active all help build connection and reduce loneliness. See a GP if loneliness is persistent and affecting your mood.

When to get help

When to see a doctor

See a GP if loneliness is persistent and affecting your mood, wellbeing or daily life, or if you have symptoms of depression or anxiety, such as persistent low mood or loss of interest. Seek urgent help if you have thoughts of harming yourself. Support, talking therapies and social prescribing can help you build connection.

999Emergency — call 999 or go to A&E
111Urgent advice — call NHS 111 or use 111 online
GPNon-urgent — see your GP or pharmacist

Not sure how urgent it is? It is always OK to call NHS 111 for advice, day or night.

Answers

Loneliness: frequently asked questions

Is loneliness bad for your health?

Loneliness is a normal human emotion and not a mental illness, but persistent loneliness can affect wellbeing — it is linked with a higher risk of depression and anxiety and can affect physical health. So it is worth taking seriously and addressing through connection, support and, if it is affecting your mood, seeing a GP.

How can I stop feeling lonely?

Reach out to existing friends and family, find ways to meet others and build new connections (groups, classes, clubs, volunteering, community activities around shared interests), and use local and online resources such as befriending schemes. Small steps help, and it takes time. See a GP if loneliness is persistent and affecting your mood — social prescribing and support can help.

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