Skin

Medicines for Melasma

Brown or grey-brown patches of increased pigmentation, usually on the face, linked to sun and hormones — harmless, and helped mainly by sun protection.

Education and reference only. This explains which medicines are used and why, in plain language — it deliberately contains no doses and is not a substitute for advice from your doctor or pharmacist. Always discuss your own treatment with a qualified clinician, and check the BNF and the product labelling for prescribing detail.

Quick answer

What is Melasma?

Melasma (also called chloasma when it occurs in pregnancy) is a common skin condition causing brown or grey-brown patches of increased pigmentation, usually on the face — typically on the cheeks, forehead, bridge of the nose, upper lip and chin, often in a fairly symmetrical pattern. It happens when the pigment-producing cells in the skin make too much pigment in these areas.

  • How it is treated: The cornerstone of managing melasma is sun protection, because sunlight is the main driver of the pigmentation, and without good protection other treatments are much less effective and the melasma tends to return.
  • Self-care: Diligent daily sun protection is the most important measure — high-factor broad-spectrum sunscreen (ideally also protecting against visible light, such as tinted mineral sunscreens), reapplied regularly, plus wide-brimmed hats and shade.
  • When to seek help: Melasma is harmless and can be self-managed with sun protection.

What it is

Melasma (also called chloasma when it occurs in pregnancy) is a common skin condition causing brown or grey-brown patches of increased pigmentation, usually on the face — typically on the cheeks, forehead, bridge of the nose, upper lip and chin, often in a fairly symmetrical pattern. It happens when the pigment-producing cells in the skin make too much pigment in these areas. It is harmless and causes no physical symptoms, but it can be cosmetically bothersome. Melasma is much more common in women and in people with darker skin tones. Its main triggers are sun exposure (ultraviolet light stimulates pigment production, and is the biggest driver) and hormonal factors — it commonly develops or worsens during pregnancy (hence "the mask of pregnancy"), and can be linked to hormonal contraception or hormone treatments. Because it is strongly influenced by sunlight, it often worsens in summer and improves in winter, and it can be persistent and prone to returning, particularly with continued sun exposure. While melasma is harmless, understanding its triggers — especially the central role of sun protection — is key to managing it.

How it is treated

The cornerstone of managing melasma is sun protection, because sunlight is the main driver of the pigmentation, and without good protection other treatments are much less effective and the melasma tends to return. This means daily use of a high-factor, broad-spectrum sunscreen (protecting against both UVA and UVB, and ideally also visible light, which can also trigger melasma — tinted mineral sunscreens can help here), reapplied regularly, along with physical measures such as wide-brimmed hats and seeking shade. Where a hormonal trigger is identified (such as hormonal contraception), reviewing this with a doctor may help, and melasma related to pregnancy often fades over the months after the birth. Beyond sun protection, treatments to lighten the pigmentation may be used, guided by a doctor or dermatologist — such as prescribed skin-lightening creams (sometimes combinations) and other approaches; these can help but need to be used carefully and alongside strict sun protection, and results can be gradual and prone to relapse. It is worth being cautious about some cosmetic treatments, as certain procedures can sometimes worsen melasma. Patience and realistic expectations help. The reassuring message is that melasma is harmless, and that diligent sun protection is the single most important and effective measure — both to improve it and to prevent it returning — alongside careful use of lightening treatments where wanted.

For this condition, these medicines

Medicine classes used for Melasma

Each links to a full, dose-free guide — what it is, how it works, who can and cannot use it, side effects, interactions and FAQs.

Beyond medication

Lifestyle and self-care

Diligent daily sun protection is the most important measure — high-factor broad-spectrum sunscreen (ideally also protecting against visible light, such as tinted mineral sunscreens), reapplied regularly, plus wide-brimmed hats and shade. Reviewing hormonal triggers with a doctor, and careful use of prescribed lightening treatments, also help.

When to get help

When to see a doctor

Melasma is harmless and can be self-managed with sun protection. See a GP or dermatologist if it is bothersome and you would like treatment, so options (and prescribed lightening treatments) can be discussed, or if you are unsure whether a pigmented patch is melasma, so it can be confirmed.

999Emergency — call 999 or go to A&E
111Urgent advice — call NHS 111 or use 111 online
GPNon-urgent — see your GP or pharmacist

Not sure how urgent it is? It is always OK to call NHS 111 for advice, day or night.

Answers

Melasma: frequently asked questions

What causes melasma?

Increased pigment production in the skin, mainly driven by sun exposure, together with hormonal factors — it commonly develops or worsens in pregnancy, and can be linked to hormonal contraception. It is more common in women and people with darker skin, and is harmless.

How is melasma treated?

The most important measure is diligent sun protection (high-factor broad-spectrum sunscreen, ideally also against visible light, plus hats and shade), as sunlight drives it. Prescribed lightening creams and other treatments can help, used carefully alongside strict sun protection. It can be prone to returning.

Sources

Where this is drawn from

  • NHS — Melasma
  • British Association of Dermatologists guidance

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