Mental health

Medicines for Psychosis

A state in which someone loses some contact with reality — for example through hallucinations or delusions — which is treatable, and where early help improves recovery.

Education and reference only. This explains which medicines are used and why, in plain language — it deliberately contains no doses and is not a substitute for advice from your doctor or pharmacist. Always discuss your own treatment with a qualified clinician, and check the BNF and the product labelling for prescribing detail.

Quick answer

What is Psychosis?

Psychosis is a mental health state in which a person perceives or interprets reality differently from those around them. Its main features are hallucinations (sensing things that are not there, such as hearing voices) and delusions (strongly held beliefs that are not based in reality), often with confused or disturbed thinking and a lack of insight that these experiences are not real.

  • How it is treated: Treatment combines medication and psychological and social support, tailored to the person and the underlying cause.
  • Self-care: Engaging with treatment and support, avoiding drugs and alcohol (which can trigger or worsen psychosis), good sleep, managing stress, and staying connected to supportive people and services all aid recovery and reduce relapse.
  • When to seek help: See a GP or mental health service if you or someone you know is experiencing hallucinations, delusions or confused thinking — early help improves recovery.

What it is

Psychosis is a mental health state in which a person perceives or interprets reality differently from those around them. Its main features are hallucinations (sensing things that are not there, such as hearing voices) and delusions (strongly held beliefs that are not based in reality), often with confused or disturbed thinking and a lack of insight that these experiences are not real. Psychosis is a symptom rather than a single illness, and can occur as part of conditions such as schizophrenia or bipolar disorder, as a result of severe depression, or be triggered by drugs, alcohol, physical illness or extreme stress. A first episode often develops in late teens or early adulthood, sometimes with an earlier phase of subtle changes. It can be frightening for the person and those around them, but it is treatable, and early treatment improves outcomes.

How it is treated

Treatment combines medication and psychological and social support, tailored to the person and the underlying cause. Antipsychotic medicines help reduce hallucinations and delusions, and talking therapies (such as CBT for psychosis) and family support help recovery and relapse prevention. Early intervention services, which support young people through a first episode of psychosis, are particularly effective and aim to help people recover and stay well. Any underlying cause — such as a mood disorder, or drug or alcohol use — is addressed, and physical health is looked after. With the right support, many people recover from an episode of psychosis and go on to live full lives, though some need longer-term support. Involving the person, respecting their experience, and providing hope are important parts of care.

For this condition, these medicines

Medicine classes used for Psychosis

Each links to a full, dose-free guide — what it is, how it works, who can and cannot use it, side effects, interactions and FAQs.

Beyond medication

Lifestyle and self-care

Engaging with treatment and support, avoiding drugs and alcohol (which can trigger or worsen psychosis), good sleep, managing stress, and staying connected to supportive people and services all aid recovery and reduce relapse.

When to get help

When to see a doctor

See a GP or mental health service if you or someone you know is experiencing hallucinations, delusions or confused thinking — early help improves recovery. Seek urgent help (crisis team, NHS 111, or 999) if there is risk to the person or others, or thoughts of suicide (Samaritans 116 123).

999Emergency — call 999 or go to A&E
111Urgent advice — call NHS 111 or use 111 online
GPNon-urgent — see your GP or pharmacist

Not sure how urgent it is? It is always OK to call NHS 111 for advice, day or night.

Answers

Psychosis: frequently asked questions

What is psychosis?

It is a state of losing some contact with reality, mainly through hallucinations (such as hearing voices) and delusions (false beliefs), often with confused thinking. It is a symptom that can occur in several conditions and is treatable.

Can people recover from psychosis?

Yes. With treatment — medication, talking therapies and support — many people recover from an episode of psychosis and live full lives. Early treatment, especially through early intervention services, improves outcomes.

Building a patient-information or formulary resource?

We create evidence-led, dose-free clinical references and decision aids for teams.

☎ Call Get a Proposal