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Faecal Elastase Test
A faecal elastase test measures an enzyme in the stool to check how well the pancreas is producing digestive enzymes.
Quick answer
Faecal Elastase Test: what it is and what the results mean
Elastase is a digestive enzyme made by the pancreas that passes through the gut into the stool. Measuring it in a stool sample shows how well the pancreas is producing enzymes for digestion.
- Why it is done: It is used to investigate symptoms of poor digestion — such as loose, greasy or pale stools, weight loss and bloating — and to help diagnose pancreatic insufficiency, for example in chronic pancreatitis or cystic fibrosis.
- Understanding results: A low elastase level suggests the pancreas is not producing enough enzymes (pancreatic insufficiency), which may be treated with enzyme replacement.
What it is
Elastase is a digestive enzyme made by the pancreas that passes through the gut into the stool. Measuring it in a stool sample shows how well the pancreas is producing enzymes for digestion.
Why it is done
It is used to investigate symptoms of poor digestion — such as loose, greasy or pale stools, weight loss and bloating — and to help diagnose pancreatic insufficiency, for example in chronic pancreatitis or cystic fibrosis.
What to expect
You collect a small stool sample at home in a container and return it to the laboratory. No special dietary preparation is usually needed, and enzyme supplements do not affect this particular test.
Understanding the results
A low elastase level suggests the pancreas is not producing enough enzymes (pancreatic insufficiency), which may be treated with enzyme replacement. A normal level makes significant insufficiency unlikely.
Good to know
Risks and limitations
It is a safe, non-invasive test. Very watery stools can dilute the sample and affect the result, and it assesses enzyme output rather than the underlying pancreatic cause, which may need imaging.
Education and reference only. This explains the test in general terms and is not medical advice. Always follow the specific instructions from the team arranging your test, and discuss your results with your clinician.
Answers
Faecal Elastase Test: frequently asked questions
What does a low faecal elastase mean?
It suggests the pancreas is not making enough digestive enzymes, a condition called pancreatic insufficiency. This can often be managed with enzyme replacement supplements taken with meals.
Do I need to stop enzyme supplements before the test?
No. The test measures human elastase, which is not affected by the animal-derived enzymes in supplements, so you can usually continue them. Your clinician will confirm any instructions.
Related tests
Other other investigations
Sources
Where this is drawn from
- NHS — Tests and treatments
- NICE — diagnostic guidance
- Association for Laboratory Medicine / relevant professional body
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