Nephrology

Creatinine Clearance (Cockcroft-Gault)

Estimated creatinine clearance for drug dosing.

Education and reference only. Not a substitute for clinical judgement, local policy or product labelling. Always verify before clinical use. Values are calculated in your browser and never stored.

When to use

Use to estimate creatinine clearance, commonly for renal drug dosing where Cockcroft-Gault is the referenced method.

Why use

Many drug dosing recommendations are based on Cockcroft-Gault rather than eGFR.

Critical actions

Creatinine must be in mg/dL (divide a µmol/L value by 88.4). Consider using ideal or adjusted body weight in obesity. Always verify against the drug's SmPC.

Evidence & references

  1. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976.

About the creator

Cockcroft & Gault

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