Therapy

Pleurodesis

Pleurodesis seals the space around the lung to stop fluid or air building up repeatedly, for example in recurrent pleural effusions.

Quick answer

Pleurodesis: what it is, why it's done and what happens

Pleurodesis deliberately sticks the two layers of the lining around the lung together, closing the space where fluid or air collects. It is often done by putting a special powder (such as talc) into the space.

  • Why it is done: It is used for repeated build-up of fluid around the lung (recurrent pleural effusion), often related to cancer, and for a recurring collapsed lung (pneumothorax), to prevent the problem coming back.
  • What happens: After draining the fluid or air, the sealing agent is introduced through a chest drain or during keyhole chest surgery (thoracoscopy).

What it is

Pleurodesis deliberately sticks the two layers of the lining around the lung together, closing the space where fluid or air collects. It is often done by putting a special powder (such as talc) into the space.

Why it is done

It is used for repeated build-up of fluid around the lung (recurrent pleural effusion), often related to cancer, and for a recurring collapsed lung (pneumothorax), to prevent the problem coming back.

What happens

After draining the fluid or air, the sealing agent is introduced through a chest drain or during keyhole chest surgery (thoracoscopy). This causes controlled inflammation that binds the layers together.

Recovery

A hospital stay while the drain is in and the space seals is usual. There may be chest pain and fever for a short time as inflammation settles. Pain relief helps, and follow-up checks the result.

Good to know

Risks and things to consider

Risks include pain, fever, infection and the pleurodesis not fully working, so fluid or air can sometimes still return. It treats the recurrent collection rather than the underlying cause.

Education and reference only. This explains the procedure in general terms and is not medical advice. Your own care, risks and recovery will be explained by the team looking after you.

Answers

Pleurodesis: frequently asked questions

Why does fluid keep coming back around my lung?

Recurrent pleural effusions are often caused by an underlying condition such as cancer or heart failure that keeps producing fluid. Pleurodesis aims to stop the fluid re-accumulating, alongside treating the cause.

Is pleurodesis painful?

The sealing process causes controlled inflammation, which can be painful for a short time and may cause a fever. Pain relief is given, and the discomfort usually settles over a few days.

Sources

Where this is drawn from

  • NHS — Tests and treatments
  • NICE — procedure and treatment guidance
  • Relevant Royal College / professional body

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