Travel vaccine

Combined Hepatitis A and B Vaccine

A combined vaccine can protect against both hepatitis A and hepatitis B in one course, convenient for travellers and others needing both.

What it protects against

It protects against both hepatitis A (spread through contaminated food and water) and hepatitis B (spread through blood and body fluids) — two viral liver infections — in a single combined course.

Who it's for

People who need protection against both infections, such as some travellers and certain risk groups, offering a convenient alternative to two separate vaccines.

How it works

It combines the inactivated hepatitis A virus and the hepatitis B surface protein, prompting protection against both, given as a course of doses.

Safety

Safety and side effects

It is safe and well tolerated, with common effects being soreness at the injection site, headache and tiredness. A travel clinic can advise on the best schedule before travel.

Education and reference only. This is general information, not a personal recommendation, and does not list doses — follow the current NHS schedule and your clinician's advice. Seek urgent help for signs of a serious allergic reaction after any vaccine.

Answers

Combined Hepatitis A and B Vaccine: frequently asked questions

Why choose a combined hepatitis A and B vaccine?

If you need protection against both, a combined vaccine means fewer injections and appointments. A travel clinic or GP can advise whether it suits your needs and timing.

How soon before travel should I start the course?

Ideally several weeks ahead, as the combined course is given over time. Accelerated schedules exist for those travelling sooner, so seek advice early.

Sources

Where this is drawn from

  • NHS — Vaccinations
  • UK Health Security Agency (UKHSA) — the Green Book
  • WHO — immunization

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